According to its statutes, the principal objectives of the TRANSFUSE Association as a membership organization are:

• to identify and recruit young professionals who should bring a fresh perspective to the discussion of future developments in Southeastern Europe;
• to develop program activities that advance international leadership within Southeastern Europe and within broader Europe and the United States;
• to nurture dialogue, cooperation and integration within Southeastern Europe as well as on the transatlantic scale, by establishing a lasting and evolving interdisciplinary network of professionals from Southeastern Europe, broader Europe and the United States;
• to promote international understanding;
• to disseminate relevant knowledge within and with regard to Southeastern Europe.

During the first General Assembly Meeting in Istanbul in April 2002, the Members of the Association agreed on the following Mission Statement:

The TRANSFUSE Association is a unique interdisciplinary network of young professionals from the Balkans, broader Europe and the United States. We bridge the gap between the needs of Southeastern Europe and international policy making by evaluating policies and approaches, identifying deficiencies, formulating priorities for regional development and generating ideas and practical recommendations for action. We contribute to building the inhternationally oriented human capital the region needs for the future. Relying on the extraordinary commitment from our members, we implement our philosophy for the region through cooperative action based on shared values and common understanding. We turn ideas into results."